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Olaparib: Uses, Dosage, Side Effects, Warnings - Drugs.com
WebNov 29, 2023 · olaparib (Lynparza) is a PARP inhibitor used to treat types of breast cancer, prostate cancer, ovarian cancer, pancreatic cancer, fallopian tube cancer, or peritoneal cancer. olaparib works by blocking a protein called PARP which helps cancer cells repair themselves, blocking PARP causes the cancer cells die.
Drugs.comOlaparib - Wikipedia
Webolaparib, sold under the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults. It is a PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair.
En.wikipedia.orgolaparib | Cancer Care Ontario
Webolaparib. Drug Formulary. About the Drug Formulary Email Drug Formulary Team. olaparib. ( oh LAP a rib ) Other Name (s): Lynparza®. Appearance: tablet. Drug Formulary information is intended for use by healthcare professionals. It …
Cancercareontario.caDRUG NAME: Olaparib - BC Cancer
WebCLASSIFICATION: molecular targeted therapy. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. MECHANISM OF ACTION: olaparib is a selective inhibitor of enzymes of the poly (ADP-ribose) polymerase family (e.g., PARP-1, PARP-2, and PARP-3).
Bccancer.bc.caLYNPARZA® (olaparib) - Official Patient Website
WebLYNPARZA is a prescription medicine used to treat adults who have: advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer with a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene.
Lynparza.comOlaparib - NCI - National Cancer Institute
Webolaparib is approved to treat: Breast cancer that is HER2 negative and has certain germline mutations in the BRCA1 or BRCA2 gene. olaparib is used after surgery in adults with: High-risk early-stage breast cancer that has been treated with chemotherapy before or …
Cancer.govCancer Care Ontario | Cancer Care Ontario
Webolaparib is a selective inhibitor of human poly (ADP-ribose) polymerase enzymes (PARP-1, PARP-2 and PARP-3) involved in DNA repair. olaparib has been shown to inhibit the growth of solid tumours, especially those deficient in BRCA function (e.g., BRCA mutation-positive ovarian tumours). Absorption.
Cancercareontario.caOlaparib (Oral Route) Description and Brand Names - Mayo Clinic
Webolaparib is used as maintenance treatment in patients with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer with a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene. Your …
Mayoclinic.orgOlaparib (Lynparza) | Cancer information | Cancer Research UK
Webolaparib is a targeted drug . It is used for a number of cancers. You might have it by itself or with another cancer drug such as bevacizumab. You might also have it as part of a clinical trial . Find more about your cancer type. It is for people who …
Cancerresearchuk.orgAdjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated …
WebJun 3, 2021 · In the OlympiA trial, we hypothesized that olaparib would provide benefit as an adjuvant therapy for patients with germline BRCA1 or BRCA2 pathogenic or likely pathogenic variant–associated early
Nejm.org