Sunitinib
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Sunitinib - Wikipedia
WEBsunitinib, sold under the brand name Sutent, is an anti-cancer medication. [2] It is a small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) in January 2006. sunitinib was the first cancer
En.wikipedia.orgSUNItinib - Cancer Care Ontario
WEBWhat it is used for. For treating some types of kidney cancer, as well as gastrointestinal stromal tumors (GIST) - a rare cancer usually affecting the stomach or intestines, and a rare type of pancreas cancer. Patient Info Sheet En. Patient Info Sheet Fr.
Cancercareontario.caSunitinib Uses, Side Effects & Warnings - Drugs.com
WEBAug 8, 2024 — What is sunitinib? sunitinib is used to treat certain types of advanced or progressive tumors of the stomach, intestines, esophagus, pancreas, or kidneys. sunitinib may also be used for purposes not listed in this medication guide.
Drugs.comSunitinib: a multitargeted receptor tyrosine kinase inhibitor in the
WEBsunitinib is an oral oxindole multitargeted kinase inhibitor that inhibits certain receptor tyrosine kinases (RTKs). These include vascular endothelial growth factor receptors (VEGFR type 1 and 2), platelet-derived growth factor receptors (PDGFR-alpha and PDGFR-beta), stem cell factor receptor (KIT) ….
Pubmed.ncbi.nlm.nih.govSunitinib: the antiangiogenic effects and beyond - PMC
WEBSep 8, 2016 — sunitinib inhibits multiple RTKs in biochemical and cell-based assays and exerts potent antiangiogenesis and antitumor effects in animal experiments. In vivo, sunitinib downregulates myeloid-derived suppressor cells (MDSC), which are thought to contribute to the antitumor effects also.
Ncbi.nlm.nih.govLearn about SUTENT® (sunitinib malate)| Official Site
WEBSee risks and benefits. Learn about the indications for SUTENT® (sunitinib malate) on the official patient website.
Sutent.comSUNItinib - Cancer Care Ontario
WEBsunitinib is a multi-targeted receptor tyrosine kinase inhibitor with effects on cell proliferation and angiogenesis. It is a potent inhibitor of platelet-derived endothelial growth factor receptors (PDGFR-α and β), vascular endothelial growth factor receptors (VEGFR-1, 2 and 3), stem cell factor receptor (KIT), Fms-like tyrosine kinase-3
Cancercareontario.caSunitinib (Oral Route) Description and Brand Names - Mayo Clinic
WEBSep 1, 2024 — sunitinib is used to treat a gastrointestinal stromal tumor (GIST) after other medicines (eg, imatinib) did not work very well. It may also be used when patients are not able to take imatinib. GIST is a group of cancer cells that start growing in the wall of the stomach, bowels, or rectum.
Mayoclinic.orgSunitinib: Uses, Interactions, Mechanism of Action - DrugBank …
WEBsunitinib is a receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Go.drugbank.comSutent: Uses, Dosage, Side Effects, Warnings - Drugs.com
WEBNov 29, 2023 — Sutent is used to treat certain types of cancer, but it is considered a targeted treatment, rather than a traditional chemotherapy drug. Sutent (sunitinib) works by inhibiting receptors that exist on the surface of some cells called receptor tyrosine kinases (RTKs).
Drugs.com