Scleroderma
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What Is Scleroderma? Symptoms & Causes| NIAMS
Jun 22, 2023 · Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic sclerosis, affects many systems in the body. This is the more serious type of scleroderma and can damage your blood vessels and internal organs, such as the heart, lungs, and kidneys.
Niams.nih.govSystemic sclerosis (scleroderma) - BMJ Best Practice
Aug 16, 2024 · Systemic sclerosis (scleroderma) is a non-contagious, chronic, multi-system disease. Initial symptoms are non-specific and include fatigue, vague musculoskeletal complaints, diffuse swelling of hands, and Raynaud's phenomenon. Aetiology and pathogenesis are unknown. Disease course is variable, but the condition rarely subsides spontaneously.
Bestpractice.bmj.comScleroderma Basics: Overview, Symptoms, and Causes
Jun 22, 2023 · What is scleroderma? scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. This inflammation leads to areas of tight, hard skin. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin.
Niams.nih.govScleroderma Basics: Diagnosis, Treatment, and Steps to Take
Jun 22, 2023 · Living with scleroderma. Living with the disease may be hard. To help, try to take an active part in treating your scleroderma. The following tips and suggestions may help. Keep warm. Dress in layers, wear gloves and socks, and avoid cold rooms and weather when possible. Try to avoid cold or wet environments that may trigger symptoms. If you
Niams.nih.govScleroderma: Diagnosis, Treatment, and Steps to Take
Jun 22, 2023 · Treatment of scleroderma. Your treatment depends on the type of scleroderma you have, your symptoms, and which tissues and organs are affected. Treatment can help control the symptoms and limit damage. Your doctor may recommend medications, including: Anti-inflammatory medications to manage pain and reduce swelling.
Niams.nih.govLimited cutaneous systemic sclerosis - BMJ Best Practice
Mar 14, 2024 · Systemic sclerosis (a type of scleroderma) is an auto-immune connective tissue disease characterised by the production of auto-antibodies (e.g., antinuclear antibody, anti-centromere antibody, and anti-topoisomerase I antibody) and the overproduction of collagen, which causes fibrosis of the skin and organs as well as vasculopathy with Raynaud's …
Bestpractice.bmj.comScleroderma: Research & Resources - National Institute of …
Jun 22, 2023 · Understanding why scleroderma can affect African Americans more severely. Evaluating how immunosuppressant and other medications can be used to help manage the symptoms and complications of scleroderma, particularly pulmonary complications. Exploring the many factors that lead to fibrosis to see if their development can be blocked.
Niams.nih.govEsclerodermia | Temas de salud | NIAMS
People with limited cutaneous scleroderma often have all or some of the symptoms that some doctors call CREST, which stands for the following symptoms: Calcinosis (KAL-sin-OH-sis), which is the formation of calcium deposits in the connective tissues, which can be detected by x-ray.
Niams.nih.govScleroderma, Fibrosis, and Autoinflammatory Disease Program
It is a heterogenous and complex disease that can be categorized as localized scleroderma (morphea) and systemic scleroderma. While etiology of scleroderma is poorly understood, abnormal vasculature, inflammation, and fibrosis are main characteristics of the disease with diverse clinical manifestations (e.g. Raynaud’s phenomenon, digital ulcers, fibrosis in skin and …
Niams.nih.govScleroderma Genomics and Health Disparities Unit | NIAMS
scleroderma (systemic sclerosis) is a chronic, multi-system, autoimmune disease characterized by progressive fibrosis of the skin and internal organs. There is a health disparity in African Americans, who have an increased prevalence of scleroderma compared to European Americans.
Niams.nih.gov