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Biofabrication strategies for 3D in vitro models and
WEBApr 26, 2018 · Biofabrication strategies can be applied to engineer 3D tissue models in vitro by mimicking the structure and function of native …
Nature.comToxicology in Vitro | Vol 52, Pages 1-398 (October 2018
WEBRead the latest articles of Toxicology in Vitro at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
Sciencedirect.comPathway-based predictive approaches for non-animal …
WEBThis paper describes the AOPs and the toolbox of in vitro and in silico models that can be used to assess the key events leading to toxicity following inhalation exposure.
Pubmed.ncbi.nlm.nih.govFrontiers | Three-Dimensional in Vitro Cell Culture …
WEBJan 23, 2018 · To date, the majority of cell cultures used in drug discovery are 2D monolayers of cells grown on planar, rigid plastic surfaces optimized for cell attachment and growth. Over the past decades, such 2D cultures …
Frontiersin.orgIn vitro DNA SCRaMbLE - Nature Communications
WEBMay 22, 2018 · Here the authors demonstrate an in vitro use of the method to generate DNA libraries for optimization of biochemical reactions.
Nature.comIn vitro and ex vivo strategies for intracellular delivery
WEBOct 12, 2016 · Here we review in vitro and ex vivo intracellular delivery approaches with a focus on mechanisms, challenges and opportunities. In particular, we emphasize membrane-disruption-based delivery
Nature.comGenomic Instabilities, Cellular Senescence, and …
WEBApr 16, 2018 · This progress has been made by three spear-headed strategies: in vitro (cell and tissue culture from various sources), in vivo (includes diverse model and non-model organisms), both can be …
Frontiersin.orgAn approved in vitro approach to preclinical safety and …
WEBPublished: October 15, 2018. https://doi.org/10.1371/journal.pone.0205491. Article. Authors. Metrics. Comments. Media Coverage. Abstract. Supporting information. Reader Comments. Figures. Abstract. Robust preclinical …
Journals.plos.orgEngineering approaches to control and design the in …
WEBJan 10, 2020 · To control this cellular distribution in vitro, various cell patterning techniques have been developed in the engineering field by employing photolithography and Micro-Electro-Mechanical Systems …
Onlinelibrary.wiley.comIn vitro digestion models suitable for foods: Opportunities for new
WEBIn vitro digestion assays simulate the physiological conditions of digestion in vivo and are useful tools for studying and understanding changes, interactions, as well as the …
Pubmed.ncbi.nlm.nih.govFrontiers | Intestinal in vitro and ex vivo Models to Study Host
WEBNov 11, 2018 · This study showed that the in vitro culture model closely resembled that of in vivo infection including mechanism release of internalized bacteria into the cytoplasm …
Frontiersin.orgIn vitro to in vivo extrapolation for high throughput prioritization
WEBMar 1, 2018 · In vitro to in vivo extrapolation (IVIVE) can be broadly defined as an approach utilizing in vitro experimental data to predict in vivo phenomena, including concentrations …
Sciencedirect.comRecent advancements and application of in vitro models for …
WEBDec 19, 2021 · The discovery of new respiratory drugs for asthma, chronic obstructive pulmonary disorder (COPD), idiopathic pulmonary fibrosis and cystic fibrosis have …
Sciencedirect.comModelling in vitro gametogenesis using induced pluripotent stem …
WEBOct 16, 2023 · In vitro gametogenesis (IVG) has been a topic of great interest in recent years not only because it allows for further exploration of mechanisms of germ cell …
Cellregeneration.springeropen.comIn vitro maturation: a committee opinion (2021) | American …
WEBThe results of in vitro maturation (IVM) investigations suggest the potential for wider clinical application. This document discusses the efficacy of IVM as reported in the published …
Asrm.orgOrganoids in cancer research - Nature Reviews Cancer
WEBApr 24, 2018 · The recent advances in in vitro 3D culture technologies, such as organoids, have opened new avenues for the development of novel, more physiological human …
Nature.comIn vitro to in vivo extrapolation for high throughput prioritization
WEBIn vitro chemical safety testing methods offer the potential for efficient and economical tools to provide relevant assessments of human health risk. To realize this potential, methods …
Ncbi.nlm.nih.govGuidance Document on Good In Vitro Method Practices …
WEBA guidance document on Good In Vitro Method Practices (GIVIMP) for the development and implementation of in vitro methods for regulatory use in human safety assessment was …
One.oecd.orgWhich concentrations are optimal for in vitro testing? - PMC
WEBAug 18, 2020 · This question has recently been discussed in an editorial of the Archives of Toxicology, where the authors pointed out that in vitro tests are usually performed at a …
Ncbi.nlm.nih.govIn vitro or not in vitro: a short journey through a long history
WEBJun 26, 2018 · With April 2018, the test guidelines for the in vitro biotransformation assays with rainbow trout hepatocytes and S9 fractions have been accepted by the OECD. A …
Ncbi.nlm.nih.govIn vitro or not in vitro: a short journey through a long history
WEBLessons learned from this research include the importance of a critical evaluation of the sensitivity, specificity and exposure conditions of in vitro assays, as well as the …
Pubmed.ncbi.nlm.nih.govEffect of high pressure homogenization on in vitro digestibility and
WEB2 days ago · In vitro protein digestibility and fermentability were affected by reformulation and by physiological digestive conditions, with lower digestibility under elderly conditions …
Pubs.rsc.orgIn vivo and in vitro sperm production: An overview of the …
WEBIn vitro maturation of testicular tissue or spermatogonial stem cells. Testis fragments can be cultured in dynamic or static systems. In the dynamic system, tissues are cultured with a …
Ncbi.nlm.nih.govJournal of Cellular Physiology | Cell Biology Journal | Wiley Online
WEB2 days ago · Abstract. Septic cardiomyopathy (SCM) is an acute cardiac dysfunction involving myocardial cell pyroptosis. TREM-1 is a known receptor on cell membrane that …
Onlinelibrary.wiley.comIn vitro to in vivo extrapolation for high throughput prioritization
WEBWe discuss properties of models that successfully generate predictions of in vivo doses from effective in vitro concentration, including the experimental systems that provide …
Pubmed.ncbi.nlm.nih.gov