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Actinium-225 - Wikipedia
WEBActinium-225 (225 Ac, Ac-225) is an isotope of actinium. It undergoes alpha decay to francium-221 with a half-life of 10 days, and is an intermediate decay product in the neptunium series (the decay chain starting at 237 Np ).
En.wikipedia.orgActinium-225: A breakthrough in cancer treatment
WEBTargeted alpha therapy (TAT) and Actinium-225. Cancer can be treated by exposing the cancerous cells to radiation (alpha, beta or gamma). Gamma radiation travels through most materials, beta radiation through fewer, and alpha radiation through very little.
Cnl.caCNL’s vision to become a world leader in Actinium-225 is coming …
WEBJun 14, 2024 · An alpha-emitting isotope, Actinium-225 can be attached to a ‘disease-targeting molecule’ that is designed to seek out and bind to cancer cells. As Actinium-225 decays, it emits high-energy alpha particles that effectively kill cancer cells, leaving nearby healthy cells unharmed in the process.
Cnl.caThe Journey of Actinium-225: How Scientists Discovered a New …
WEBJun 20, 2018 · It gives off a faint blue glow, a sign of its radioactivity. While the energy and subatomic particles it emits can damage human cells, they can also kill some of our most stubborn cancers. This substance is actinium-225. Fortunately, scientists have figured out how to harness actinium-225's power for good.
Energy.govTRIUMF and CNL announce first joint production run of actinium-225
WEBAn alpha-emitting isotope with a short half-life, actinium-225 can be combined with a protein or antibody that specifically targets and kills cancer cells; the cancer-specific molecules seek out and destroy only cancer cells while leaving the surrounding healthy tissue unharmed.
Triumf.caCNL announces project to significantly increase production of rare
WEBJun 14, 2024 · Agreement between CNL and the Sylvia Fedoruk Centre for Nuclear Innovation will increase CNL’s production of Actinium-225 by several orders of magnitude, enabling larger scale clinical trials.
Cnl.caMultiple Production Methods Underway to Provide Actinium-225
WEBDiscovered in 1947 by a team at Argonne National Laboratory and an independent Canadian research team, actinium-225 (Ac-225) undergoes alpha decay to francium-221 with a half-life of 10 days. For this reason, the isotope is being evaluated as an ideal candidate for use in medical applications.
Isotopes.govActinium-225 targeted alpha particle therapy for prostate cancer
WEBMay 11, 2024 · Actinium-225 (225 Ac) is a promising alpha-emitting radionuclide for prostate cancer targeted radiotherapy. 225 Ac has a half-life of 9.92 days, during which it decays through a series of short-lived alpha and beta-emitting daughters (Figure Figure3 3).
Ncbi.nlm.nih.govActinium-225-PSMA radioligand therapy of metastatic castration
WEBActinium-225 (225 Ac) prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) is a novel therapy for metastatic castration-resistant prostate cancer (mCRPC).
Thelancet.comProduction and Quality Control of Actinium-225 …
WEBThis publication includes existing experiences, lessons learned, challenges and future developments in the production of Ac-225 radiopharmaceuticals for Targeted Alpha Therapy (TAT).
Iaea.org