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Adiponectin - Wikipedia
Adiponectin is a 244-amino-acid-long polypeptide (protein). It has four distinct regions: The first is a short signal sequence that targets the hormone for secretion outside the cell; next is a short region that varies between species; the third is a 65-amino acid region with similarity to collagenous proteins; the last is a globular domain. Overall, this protein shows similarity to the complement 1Q factors (C1Q), but when the three-dimensional structure of the globular region …
En.wikipedia.orgAdiponectin: Role in Physiology and Pathophysiology - PMC
WEBSep 3, 2020 · Adiponectin, an adipokine secreted by adipocytes, is a well-known homeostatic factor for regulating glucose levels, lipid metabolism, and insulin sensitivity …
Ncbi.nlm.nih.govAdiponectin: Structure, Physiological Functions, Role in …
WEBApr 2, 2021 · Adiponectin is a circulating hormone secreted by adipose tissue which exerts protective effects against inflammation and can positively modulate the endocrine …
Ncbi.nlm.nih.govAdiponectin, a Therapeutic Target for Obesity, Diabetes, and
WEBJun 21, 2017 · The current knowledge on regulation and function of adiponectin in obesity, insulin resistance, and cardiovascular disease is summarized in this review. Keywords: …
Ncbi.nlm.nih.govMetabolic Messengers: adiponectin - Nature Metabolism
WEBMar 14, 2019 · Adiponectin, first described in the mid-1990s, is one of the most widely studied adipokines to date. Studies of its regulation, biogenesis and physiological effects have yielded great insight and
Nature.comAdiponectin: Role in Physiology and Pathophysiology
WEBSep 3, 2020 · Adiponectin, an adipokine secreted by adipocytes, is a well-known homeostatic factor for regulating glucose levels, lipid metabolism, and insulin sensitivity …
Pubmed.ncbi.nlm.nih.govAdiponectin: Structure, Physiological Functions, Role …
WEBApr 2, 2021 · Adiponectin is a circulating hormone secreted by adipose tissue which exerts protective effects against inflammation and can positively modulate the endocrine system, by enhancing insulin …
Mdpi.comAdiponectin: Structure, Physiological Functions, Role in …
WEBApr 2, 2021 · Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular weight of 28 kDa) is a cytokine that is secreted from adipose tissues …
Pubmed.ncbi.nlm.nih.govAdiponectin Regulation and Function - PubMed
WEBJun 18, 2018 · Adiponectin stimulates fatty acid oxidation in skeletal muscle and inhibits glucose production in the liver, resulting in an improvement in whole-body energy …
Pubmed.ncbi.nlm.nih.govBiochemistry, Adiponectin - StatPearls - NCBI Bookshelf
WEBJul 30, 2023 · Adiponectin is the most abundant peptide hormone secreted by white adipocytes. Since discovering adiponectin in the 1990s, it has become a widely accepted biomarker for obesity-related diseases …
Ncbi.nlm.nih.govAdiponectin: friend or foe in obesity and inflammation - De Gruyter
WEBAdiponectin, the most representative adipokine, is a 30 kDa protein predominantly secreted by adipocytes and targets a variety of cell types or tissue/organs by binding to its own …
Degruyter.comAdiponectin: a manifold therapeutic target for metabolic syndrome
WEBJun 23, 2014 · Adiponectin stimulates phosphorylation and AMP (adenosin mono phosphate) kinase activation, exerting direct effects on vascular endothelium, …
Cardiab.biomedcentral.comAdiponectin: More Than Just Another Fat Cell Hormone?
WEBAug 1, 2003 · The view of the adipocyte as simply a storage depot for fat is no longer tenable. Among the various “adipocytokines,” adiponectin, which is an abundant …
Diabetesjournals.orgAdiponectin signalling in bone homeostasis, with age and in disease
WEBJan 7, 2021 · Adiponectin is the most abundant circulating adipokine and is primarily involved in glucose metabolism and insulin resistance. Within the bone, osteoblasts and …
Nature.comThe Role of Adipokines in Health and Disease - PMC
WEBApr 27, 2023 · Adipokines are bioactive molecules secreted by adipose tissue that have various effects on health and disease. They play important roles in regulating …
Ncbi.nlm.nih.govAdiponectin, a Therapeutic Target for Obesity, Diabetes, and
WEBAdiponectin is the most abundant peptide secreted by adipocytes, whose reduction plays a central role in obesity-related diseases, including insulin resistance/type 2 diabetes and …
Mdpi.comAdipokines (Leptin, Adiponectin, Resistin) Differentially Regulate …
WEBMar 6, 2017 · Introduction. Adipose tissue is a metabolically active organ that secretes multiple adipokines, including classical leptin, adiponectin, and resistin, which exert …
Nature.comAdiponectin: a manifold therapeutic target for metabolic - PubMed
WEBJun 23, 2014 · We summarize here the current knowledge about the influence of adiponectin on insulin sensitivity and endothelial function, discussing its forthcoming …
Pubmed.ncbi.nlm.nih.govAdiponectin: The Potential Regulator and Therapeutic Target of …
WEBSep 3, 2020 · Adiponectin is a benign adipokine that sensitizes the insulin receptor signaling pathway and suppresses inflammation. It has been shown to be inversely correlated …
Ncbi.nlm.nih.govAdiponectin, Leptin and Cardiovascular Disorders
WEBJan 7, 2021 · The pathogenesis of cardiovascular dysfunction is highly complex. Two of the most widely studied adipokines, adiponectin and leptin, are important players in …
Ahajournals.orgAdiponectin--a key adipokine in the metabolic syndrome
WEBAdiponectin is a recently described adipokine that has been recognized as a key regulator of insulin sensitivity and tissue inflammation. It is produced by adipose tissue (white …
Pubmed.ncbi.nlm.nih.govAdiponectin: an adipokine with protective features against …
WEBJun 30, 2014 · Adiponectin is one of the most abundant peptide hormones derived from adipose tissue. This protein plays a major role in glucose and lipid metabolism and …
Ncbi.nlm.nih.gov